Apolipoprotein E gene polymorphism in Greek children with nephrotic syndrome

Vaia Papadopoulou, Kali Makedou, Dimitra Papadopoulou, Anagnostis Argyriou, Magdalini Gatzola, Areti Hitoglou

Abstract


Apolipoprotein E (ApoE) genotypes were determined for children with nephrotic syndrome (NS) (study group, N=17) and control group (N=31). In controls, ε3/ε3 was prominent. In study group, ε2 allele was present in contrast to con­trols. Hypercholesterolemia seems related to apoE genes polymorphism. Genotyping could predict the clinical course of NS.


Keywords


ApoE, Genotype, Nephrotic syndrome, Children

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